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Anti-PKC alpha/beta/gamma (Polyclonal), ALEXA Fluor 594

Anti-PKC alpha/beta/gamma (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePKC alpha/beta/gamma
SpecificityThis antibody reacts specifically with PKC alpha/beta/gamma
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Cell membrane, Mitochondrion, Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human PKC alpha
Gene ID5578
Swiss ProtP17252
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Dog, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1), This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation, and solute transport, cell cell adhesion, cell extracellular matrix adhesion, cell survival and transcriptional regulation, development, diacylglycerol, differentiation, migration, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ25513 DKFZp547J199 IFITMD1 FICCA DSPB3 PKC EKD1
Also known asPKC alpha/beta/gamma Polyclonal Antibody
Other nameAnti-PKC alpha/beta/gamma Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPKC alpha/beta/gamma
Short nameAnti-PKC alpha/beta/gamma (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PKC a/b/g (polyclonal)
Alternative techniquepolyclonals
Identity 30500
Gene PRRT2
Long gene name proline rich transmembrane protein 2
Synonyms gene ICCA DYT10
Synonyms gene name infantile convulsions and paroxysmal choreoathetosis dystonia 10 proline-rich transmembrane protein 2
Synonyms name interferon induced transmembrane protein domain containing 1
Locus 16p11, 2
Discovery year 2005-11-25
GenBank acession BC011405
Entrez gene record 112476
Pubmed identfication 22101681 22243967
RefSeq identity NM_145239
Classification Proline rich transmembrane proteins
Havana BLAST/BLAT OTTHUMG00000177142

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