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Anti-PKC gamma/SCA14 (Polyclonal), ALEXA Fluor 594

Anti-PKC gamma/SCA14 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePKC gamma/SCA14
SpecificityThis antibody reacts specifically with PKC gamma/SCA14
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PKC gamma/SCA14
Gene ID5582
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14), Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells, It has been demonstrated that several neuronal functions, Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development, PKC also serve as major receptors for phorbol esters, PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways, PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons, The protein encoded by this gene is one of the PKC family members, There have been at least 12 different PKC isoforms identified in humans to date including alpha, a class of tumor promoters, and mu, beta I, beta II, delta, epsilon, eta, gamma, including long term potentiation (LTP) and long term depression (LTD), iota, lambda, specifically require this kinase, theta, zeta, Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PKCC MGC57564
Also known asPKC gamma/SCA14 Polyclonal Antibody
Other nameAnti-PKC gamma/SCA14 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPKC gamma/SCA14
Short nameAnti-PKC gamma/SCA14 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PKC g/SCA14 (polyclonal)
Alternative techniquepolyclonals
Identity 9402
Gene PRKCG
Long gene name protein kinase C gamma
Synonyms gene PKCG SCA14
Synonyms gene name gamma , protein kinase C
Synonyms name PKC-gamma
Locus 19q13, 42
Discovery year 1991-08-02
GenBank acession M13977
Entrez gene record 5582
Pubmed identfication 8432525 3755548
RefSeq identity NM_002739
Classification C2 domain containing protein kinases
Havana BLAST/BLAT OTTHUMG00000064846
Locus Specific Databases LRG_669 , Mutations of the Protein Kinase C &, #947

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