Name : Anti-PLAGL1/ZAC1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4814519204
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PLAGL1/ZAC1 |
| Specificity | This antibody reacts specifically with PLAGL1/ZAC1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human PLAGL1 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters, In addition, It has been shown to have anti-proliferative properties, Many transcript variants differing in the 5' UTR and encoding two different isoforms, Oct 2010], This gene is imprinted, [provided by RefSeq, and thus thought to function as a tumor suppressor, biallelic expression has been noted in peripheral blood leucocytes, have been found for this gene, however, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM), with preferential expression of the paternal allele in many tissues, This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | ZAC LOT1 |
| Also known as | PLAGL1/ZAC1 Polyclonal Antibody |
| Other name | Anti-PLAGL1/ZAC1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PLAGL1/ZAC1 |
| Short name | Anti-PLAGL1/ZAC1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-pleiomorphic adenoma gene-like 1/ZAC1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BT, LOT1 and ZAC and ZAC1, PLAGL1 and IDBG-97390 and ENSG00000118495 and 5325, Plagl1 and IDBG-134075 and ENSMUSG00000019817 and 22634, metal ion binding, nuclei, this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001228 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0030154 and cell differentiation and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001228: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0005515: protein binding and also this GO :0046872: metal ion binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001228: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0005515: protein binding, this GO :0046872: metal ion binding, 37603 and IDBG-647056 and ENSBTAG00000026523 and 539761, pleiomorphic adenoma gene-like 1 |
| Identity | 9046 |
| Gene | PLAGL1 |
| Long gene name | PLAG1 like zinc finger 1 |
| Synonyms gene name | pleiomorphic adenoma gene-like 1 |
| Locus | 6q24, 2 |
| Discovery year | 1998-02-17 |
| GenBank acession | U81992 |
| Entrez gene record | 5325 |
| Pubmed identfication | 9722527 9671765 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000015738 |
| Locus Specific Databases | LRG_1101 |