Name : Anti-PLCL1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5694166108
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PLCL1 |
| Specificity | PLCL1, This antibody may exhibit a slight secondary cross-reactivity with PLCL2 due to a 69% non-sequential sequence similarity over the immunogen range |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human PLCL1 |
| Gene ID | 5334 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as an inhibitor of PPP1C, Component in the dependent endocytosis process of GABA A receptor (By similarity), Its aberrant expression could contribute to the genesis and progression of lung carcinoma, Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition, Shows no PLC activity to phosphatidylinositol 4, 5-bisphosphate and sphatidylinositol, PLCL1 is involved an inositol phospholipid based intracellular signaling cascade |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PLC-L PLCL PRIP PPP1R127 |
| Also known as | PLCL1 Polyclonal Antibody |
| Other name | Anti-PLCL1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PLCL1 |
| Short name | Anti-PLCL1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-PLCL1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 9063 |
| Gene | PLCL1 |
| Long gene name | phospholipase C like 1 |
| Synonyms gene | PLCE |
| Synonyms gene name | epsilon phospholipase C-like 1 , phospholipase C |
| Synonyms name | but catalytically inactive protein protein phosphatase 1, phospholipase C related, regulatory subunit 127 |
| Locus | 2q33, 1 |
| Discovery year | 1995-12-12 |
| GenBank acession | D42108 |
| Entrez gene record | 5334 |
| Pubmed identfication | 7633416 |
| RefSeq identity | NM_006226 |
| Classification | Protein phosphatase 1 regulatory subunits C2 domain containing phospholipases |
| Havana BLAST/BLAT | OTTHUMG00000132750 |