Name : Anti-PLK1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2114780501
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PLK1 |
| Specificity | This antibody reacts specifically with PLK1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus |
| Antigen Source | KLH conjugated synthetic peptide derived from human PLK1 |
| Gene ID | 5347 |
| Swiss Prot | P53350 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies, PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa, PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase, PLK1 is modified by phosphorylation at Threonine 210, PLK1 may also be required for cell division, cdc5/polo subfamily, PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | PLK1 Polyclonal Antibody |
| Other name | Anti-PLK1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PLK1 |
| Short name | Anti-PLK1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-PLK1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 9077 |
| Gene | PLK1 |
| Long gene name | polo like kinase 1 |
| Synonyms gene | PLK |
| Synonyms gene name | polo-like kinase (Drosophila) polo-like kinase 1 |
| Locus | 16p12, 2 |
| Discovery year | 1994-07-25 |
| Entrez gene record | 5347 |
| Pubmed identfication | 8127874 |
| RefSeq identity | NM_005030 |
| Havana BLAST/BLAT | OTTHUMG00000096984 |