Anti-PMP22 (Polyclonal), ALEXA Fluor 594

Anti-PMP22 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	PMP22
Specificity	This antibody reacts specifically with PMP22
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human PMP-22
Gene ID	5376
Swiss Prot	Q01453
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Alterations in the level of this protein cause several genetic human diseases, If one copy of the gene is deleted, If the protein is duplicated, In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration, patients develop Charcot Marie Tooth disease, they suffer from the inherited tendency to pressure palsies, PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	PMP22
Also known as	PMP22 Polyclonal Antibody
Other name	Anti-PMP22 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	PMP22
Short name	Anti-PMP22 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-PMP22 (polyclonal)
Alternative technique	polyclonals
Identity	9716
Gene	PXMP2
Long gene name	peroxisomal membrane protein 2
Synonyms gene name	22kDa , peroxisomal membrane protein 2 (22kD) peroxisomal membrane protein 2
Locus	12q24, 33
Discovery year	1992-03-03
Entrez gene record	5827
Pubmed identfication	11590176
RefSeq identity	NM_018663
Havana BLAST/BLAT	OTTHUMG00000168019

Anti-PMP22 (Polyclonal), ALEXA Fluor 594

Anti-PMP22 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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