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Anti-Polycystin 1 (Polyclonal), ALEXA Fluor 594

Anti-Polycystin 1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePolycystin 1
SpecificityThis antibody reacts specifically with Polycystin 1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Polycystin 1
Gene ID5310
Swiss ProtP98161
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a regulator of cilium length, Involved in adhesive protein-protein and protein-carbohydrate interactions, Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium, May be an ion-channel regulator, The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling, leads to cilium shortening and thus decreases flow-induced signaling (By similarity), together with PKD2, which decreases intracellular cAMP, Involved in renal tubulogenesis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asPolycystin 1 Polyclonal Antibody
Other nameAnti-Polycystin 1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPolycystin 1
Short nameAnti-Polycystin 1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Polycystin 1 (polyclonal)
Alternative techniquepolyclonals
Identity 21716
Gene PKD1L3
Long gene name polycystin 1 like 3, transient receptor potential channel interacting
Synonyms gene name polycystic kidney disease 1-like 3
Locus 16q22, 2
Discovery year 2003-08-05
GenBank acession AY164485
Entrez gene record 342372
Pubmed identfication 12782129 20538909
RefSeq identity NM_181536
Classification C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000166114

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