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Anti-POMT1 (Polyclonal), ALEXA Fluor 594

Anti-POMT1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePOMT1
SpecificityThis antibody reacts specifically with POMT1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human POMT1
Gene ID10585
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), Enzymatic activity is dependent on co expression of POMT1 with POMT2, Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours, Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues, Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction, a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life, which is associated with mild mental retardation, POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LGMD2K
Also known asPOMT1 Polyclonal Antibody
Other nameAnti-POMT1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPOMT1
Short nameAnti-POMT1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-POMT1 (polyclonal)
Alternative techniquepolyclonals
Identity 9202
Gene POMT1
Long gene name protein O-mannosyltransferase 1
Synonyms name dolichyl-phosphate-mannose-protein mannosyltransferase
Locus 9q34, 13
Discovery year 1999-06-25
GenBank acession AF095136
Entrez gene record 10585
Pubmed identfication 10366449
RefSeq identity NM_007171
Classification Dolichyl D-mannosyl phosphate dependent mannosyltransferases
Havana BLAST/BLAT OTTHUMG00000020826
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_842

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