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Anti-PPAPDC3 (Polyclonal), ALEXA Fluor 594

Anti-PPAPDC3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePPAPDC3
SpecificityThis antibody reacts specifically with PPAPDC3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PPAPDC3
Gene ID84814
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Has no detectable enzymatic activity, It is a member of the PAP2 superfamily of phosphatases and haloperoxidases, Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis, PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR, PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues, also known as nuclear envelope transmembrane protein 39 (NET39), in part through effects on MTOR signaling, was initially discovered in an in silico screen for secreted or membrane proteins, PPAPDC3, Plays a role as negative regulator of myoblast differentiation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MGC12921 FLJ14662 NET39
Also known asPPAPDC3 Polyclonal Antibody
Other nameAnti-PPAPDC3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPPAPDC3
Short nameAnti-PPAPDC3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PPAPDC3 (polyclonal)
Alternative techniquepolyclonals
Identity 28174
Gene PLPP7
Long gene name phospholipid phosphatase 7 (inactive)
Synonyms gene C9orf67 PPAPDC3
Synonyms gene name chromosome 9 open reading frame 67 phosphatidic acid phosphatase type 2 domain containing 3
Synonyms name nuclear envelope transmembrane protein NET39
Locus 9q34, 13
Discovery year 2004-01-06
GenBank acession AK027568
Entrez gene record 84814
Pubmed identfication 12958361
RefSeq identity NM_032728
Classification Phospholipid phosphatases
Havana BLAST/BLAT OTTHUMG00000020822

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