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Anti-PPAR alpha (Polyclonal), ALEXA Fluor 594

Anti-PPAR alpha (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePPAR alpha
SpecificityThis antibody reacts specifically with PPAR alpha
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human PPAR alpha
Gene ID5465
Swiss ProtQ07869
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activated by oleylethanolamide, Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC), Functions as transcription activator for the ACOX1 and P450 genes, Key regulator of lipid metabolism, May be required for the propagation of clock information to metabolic pathways regulated by PER2, Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids, Regulates the peroxisomal beta-oxidation pathway of fatty acids, Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2, a naturally occurring lipid that regulates satiety, Ligand-activated transcription factor
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms hPPAR NR1C1
Also known asPPAR alpha Polyclonal Antibody
Other nameAnti-PPAR alpha Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPPAR alpha
Short nameAnti-PPAR alpha (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PPAR a (polyclonal)
Alternative techniquepolyclonals
Identity 9232
Gene PPARA
Long gene name peroxisome proliferator activated receptor alpha
Synonyms gene PPAR
Synonyms gene name alpha peroxisome proliferator-activated receptor alpha , peroxisome proliferative activated receptor
Locus 22q13, 31
Discovery year 1993-11-01
GenBank acession L02932
Entrez gene record 5465
Pubmed identfication 7684926 10591208
RefSeq identity NM_001001928
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000150443

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