Anti-PR3 (Polyclonal), ALEXA Fluor 594

Anti-PR3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	PR3
Specificity	This antibody reacts specifically with PR3
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human PR3
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	All three genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation, It is closely related to two others: Neutrophil Elastase and azurocidin, P29 or myeloblastin), PR3 is a neutrophil protein which is able to cleave elastin and is involved in proliferation of human leukemia cells, PR3 is expressed specifically in immature myeloid cells and is a G-CSF-responsive protein critical to factor-independent growth, The antigen responsible for this disease is Proteinase 3 (PR3, The genes for all three of the related serine protease family members are located in a cluster on the tip of the short arm of human chromosome 19, necrotizing glomerulonephritis and pulmonary capillaritis, which is one of the antibiotic proteins of neutrophilic granules belonging to the serine protease family, which most often affect the upper and lower airways and are associated with vasculitis, The major features of Wegener granulomatosis are necrotizing granulomatous lesions
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	AGP 7, AGP7, AGP7 serine proteinase, Azurophil Granule Protein 7, C ANCA antigen, C-ANCA antigen, EC 3, Leukocyte proteinase 3, MBN, MBT WEGENER AUTOANTIGEN, Myeloblastin, NP 4, NP-4, NP4, Neutrophil proteinase 4, P29, PR 3, PR-3, PR3, PRTN 3, PRTN3_HUMAN, Proteinase3, Prtn3, Serine proteinase neutrophil Wegener granulomatosis autoantigen, Wegener autoantigen, 4, 21, 76, ACPA
Also known as	PR3 Polyclonal Antibody
Other name	Anti-PR3 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	PR3
Short name	Anti-PR3 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-PR3 (polyclonal)
Alternative technique	polyclonals

Anti-PR3 (Polyclonal), ALEXA Fluor 594

Anti-PR3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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