Name : Anti-PRDX1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5996525113
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PRDX1 |
| Specificity | This antibody reacts specifically with PRDX1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human PRDX1 |
| Gene ID | 5052 |
| Swiss Prot | Q06830 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | May play an important role in eliminating peroxides generated during metabolism, Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2), Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity), Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin, Involved in redox regulation of the cell |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | NKEFA |
| Also known as | PRDX1 Polyclonal Antibody |
| Other name | Anti-PRDX1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PRDX1 |
| Short name | Anti-PRDX1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-peroxiredoxin 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | MSP23 and NKEF-A and NKEFA and PAG and PAGA and PAGB and PRX1 and PRXI and TDPX2, PRDX1 and IDBG-640075 and ENSBTAG00000003642 and 281997, PRDX1 and IDBG-97953 and ENSG00000117450 and 5052, Prdx1 and IDBG-178542 and ENSMUSG00000028691 and 18477, nuclei, peroxiredoxin activity, this GO :0000302 and response to reactive oxygen species and biological process this GO :0001501 and skeletal system development and biological process this GO :0001895 and retina homeostasis and biological process this GO :0004601 and peroxidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005719 and nuclear euchromatin and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0006979 and response to oxidative stress and biological process this GO :0008283 and cell proliferation and biological process this GO :0008379 and thioredoxin peroxidase activity and molecular function this GO :0016209 and antioxidant activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0020037 and heme binding and molecular function this GO :0032872 and regulation of stress-activated MAPK cascade and biological process this GO :0034101 and erythrocyte homeostasis and biological process this GO :0042267 and natural killer cell mediated cytotoxicity and biological process this GO :0042345 and regulation of NF-kappaB import into nucleus and biological process this GO :0042470 and melanosome and cellular component this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051920 and peroxiredoxin activity and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004601: peroxidase activity, this GO :0004601: peroxidase activity and also this GO :0005515: protein binding and also this GO :0008379: thioredoxin peroxidase activity and also this GO :0016209: antioxidant activity and also this GO :0016491: oxidoreductase activity and also this GO :0020037: heme binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0044822: poly(A) RNA binding and also this GO :0051920: peroxiredoxin activity, this GO :0005515: protein binding, this GO :0008379: thioredoxin peroxidase activity, this GO :0016209: antioxidant activity, this GO :0016491: oxidoreductase activity, this GO :0020037: heme binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0044822: poly(A) RNA binding, this GO :0051920: peroxiredoxin activity, peroxiredoxin 1 |
| Identity | 9352 |
| Gene | PRDX1 |
| Long gene name | peroxiredoxin 1 |
| Synonyms gene | PAGA |
| Locus | 1p34, 1 |
| Discovery year | 1993-11-01 |
| GenBank acession | BC021683 |
| Entrez gene record | 5052 |
| Pubmed identfication | 8496166 |
| RefSeq identity | NM_181697 |
| Classification | Peroxiredoxins |
| Havana BLAST/BLAT | OTTHUMG00000007738 |