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Anti-PRK1 (Thr774)/PRK2 (Thr816), ALEXA Fluor 594

Anti-PRK1 (Thr774)/PRK2 (Thr816), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePRK1 Thr774 + PRK2 Thr816
SpecificityThis antibody reacts specifically with PRK1 (Thr774)/PRK2 (Thr816)
ModificationPhosphorylation
Modification siteThr816
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774
Gene ID5585
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information EG-VEGF, EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner, EG-VEGF possesses an HIF-1 binding site, Expression of EG-VEGF is often complementary to the expression of VEGF, It is expressed primarily in one type of tissue and acts selectively on one type of endothelium, adrenal and placenta), and fenestration in capillary endothelial cells derived from endocrine glands, its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, leading to proliferation, migration, migration and survival of responsive endothelial cells , possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, suggesting that these molecules function in a coordinated manner, testis, Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PRK2 Pak-2 STK7
Also known asPRK1 (Thr774)/PRK2 (Thr816) Antibody
Other nameAnti-PRK1 (Thr774)/PRK2 (Thr816)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetPRK1 (Thr774)/PRK2 (Thr816)
Short nameAnti-PRK1 (Thr774)/PRK2 (Thr816) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PRK1 (Thr774)/PRK2 (Thr816)
Identity 9406
Gene PKN2
Long gene name protein kinase N2
Synonyms gene PRKCL2
Synonyms gene name protein kinase C-like 2
Synonyms name cardiolipin-activated protein kinase Pak2
Locus 1p22, 2
Discovery year 1997-10-10
GenBank acession U33052
Entrez gene record 5586
Pubmed identfication 7988719 7851406
RefSeq identity NM_006256
Classification C2 domain containing protein kinases
Havana BLAST/BLAT OTTHUMG00000010074

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