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Anti-PRKACB(Thr198) (Polyclonal), ALEXA Fluor 594
Anti-PRKACB(Thr198) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516
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BIOSS POLYCLONAL ANTIBODIES
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516
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PRKACB Thr198 |
| Specificity | This antibody reacts specifically with PRKACB(Thr198) |
| Modification | Phosphorylation |
| Modification site | Thr198 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human PRKACB around the phosphorylation site of Thr198 |
| Gene ID | 5567 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits, cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits, cAMP exerts its effects by activating the cAMP-dependent protein kinase, cAMP is a signaling molecule important for a variety of cellular functions, which transduces the signal through phosphorylation of different target proteins, PKA alpha + beta (catalytic subunits) (phospho Thr198), PRKACA and PRKACB are members of the Ser/Thr protein kinase family and are a catalytic subunit of cAMP-dependent protein kinase |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PKACb |
| Also known as | PRKACB(Thr198) Polyclonal Antibody |
| Other name | Anti-PRKACB(Thr198) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PRKACB(Thr198) |
| Short name | Anti-PRKACB(Thr198) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, b(Thr198) (polyclonal), catalytic, cathelicidin antimicrobial peptide-dependent, antibody to-protein phosphorylation catalyst |
| Alternative technique | polyclonals |
| Alternative to gene target | PKA C-beta and PKACB, PRKACB and IDBG-637426 and ENSBTAG00000011953 and 282323, PRKACB and IDBG-99931 and ENSG00000142875 and 5567, Prkacb and IDBG-199561 and ENSMUSG00000005034 and 18749, beta, cAMP-dependent, catalytic, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004691 and cAMP-dependent protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005952 and cAMP-dependent protein kinase complex and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006006 and glucose metabolic process and biological process this GO :0006094 and gluconeogenesis and biological process this GO :0006112 and energy reserve metabolic process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006833 and water transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007596 and blood coagulation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004691: cAMP-dependent protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004691: cAMP-dependent protein kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0031625: ubiquitin protein ligase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031625: ubiquitin protein ligase binding, transferring phosphorus-containing groups and molecular function this GO :0019433 and triglyceride catabolic process and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0034199 and activation of protein kinase A activity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050796 and regulation of insulin secretion and biological process this GO :0051447 and negative regulation of meiotic cell cycle and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070613 and regulation of protein processing and biological process this GO :0071377 and cellular response to gluca this GO n stimulus and biological process this GO :0097338 and response to clozapine and biological process this GO :0097546 and ciliary base and cellular component this GO :1901621 and negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning and biological process, protein kinase |
| Identity | 9381 |
| Gene | PRKACB |
| Long gene name | protein kinase cAMP-activated catalytic subunit beta |
| Synonyms gene name | beta catalytic subunit , beta protein kinase, cAMP-dependent, cAMP-dependent, catalytic, protein kinase |
| Locus | 1p31, 1 |
| Discovery year | 2001-06-22 |
| GenBank acession | BC035058 |
| Entrez gene record | 5567 |
| RefSeq identity | NM_182948 |
| Havana BLAST/BLAT | OTTHUMG00000009975 |