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Anti-PRKCQ(Ser676) (Polyclonal), ALEXA Fluor 594
Anti-PRKCQ(Ser676) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516
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BIOSS POLYCLONAL ANTIBODIES
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516
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PRKCQ Ser676 |
| Specificity | This antibody reacts specifically with PRKCQ(Ser676) |
| Modification | Phosphorylation |
| Modification site | Ser676 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human PRKCQ around the phosphorylation site of Ser676 |
| Gene ID | 5588 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Essential for T-cell receptor (TCR)-mediated T-cell activation, Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes, PKC also serves as the receptor for phorbol esters, PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins, Required for interleukin-2 (IL2) production, a class of tumor promoters, but is dispensable during TCR-dependent thymocyte development, phospholipid-dependent, serine- and threonine-specific enzyme, This is a calcium-independent |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | PRKCQ(Ser676) Polyclonal Antibody |
| Other name | Anti-PRKCQ(Ser676) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PRKCQ(Ser676) |
| Short name | Anti-PRKCQ(Ser676) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, theta(Ser676) (polyclonal), antibody to-protein kinase C |
| Alternative technique | polyclonals |
| Alternative to gene target | Cell surfaces, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0007603 and phototransduction, PRKCQ and IDBG-51302 and ENSG00000065675 and 5588, PRKCQ and IDBG-637023 and ENSBTAG00000010664 and 505901, Prkcq and IDBG-136196 and ENSMUSG00000026778 and 18761, nPKC-theta and PRKCT, theta, this GO :0001558 and regulation of cell growth and biological process this GO :0001772 and immunological synapse and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004697 and protein kinase C activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004697: protein kinase C activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004697: protein kinase C activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004842: ubiquitin-protein transferase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0022400 and regulation of rhodopsin mediated signaling pathway and biological process this GO :0030168 and platelet activation and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070233 and negative regulation of T cell apoptotic process and biological process this GO :0090330 and regulation of platelet aggregation and biological process this GO :2000318 and positive regulation of T-helper 17 type immune response and biological process this GO :2000570 and positive regulation of T-helper 2 cell activation and biological process, visible light and biological process this GO :0016056 and rhodopsin mediated signaling pathway and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016772 and transferase activity, protein kinase C |
| Identity | 9410 |
| Gene | PRKCQ |
| Long gene name | protein kinase C theta |
| Synonyms gene name | protein kinase C, theta |
| Locus | 10p15, 1 |
| Discovery year | 1992-12-14 |
| GenBank acession | L07032 |
| Entrez gene record | 5588 |
| Pubmed identfication | 8444877 |
| RefSeq identity | NM_006257 |
| Classification | C2 domain containing protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000017623 |