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Anti-PRMT4 (Polyclonal), ALEXA Fluor 594

Anti-PRMT4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePRMT4
SpecificityThis antibody reacts specifically with PRMT4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PRMT4
Gene ID10498
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information At least two transcript variants encoding the same protein have been found for this gene (from EntrezGene), It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence, It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer, P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence, The microsatellite is polymorphic, This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death, which are enzymes involved in cellular responses to oxidative stresses and irradiation, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53, The protein encoded by this gene is similar to oxidoreductases
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PRMT4
Also known asPRMT4 Polyclonal Antibody
Other nameAnti-PRMT4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPRMT4
Short nameAnti-PRMT4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PRMT4 (polyclonal)
Alternative techniquepolyclonals
Identity 23393
Gene CARM1
Long gene name coactivator associated arginine methyltransferase 1
Locus 19p13, 2
Discovery year 2003-11-14
GenBank acession AF055027
Entrez gene record 10498
Pubmed identfication 10381882 11724789
RefSeq identity NM_199141
Classification Protein arginine methyltransferases
Havana BLAST/BLAT OTTHUMG00000180699

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