Anti-Prominin 2 (Polyclonal), ALEXA Fluor 594

Anti-Prominin 2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Prominin 2
Specificity	This antibody reacts specifically with Prominin 2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human Prominin 2
Gene ID	150696
Swiss Prot	Q8N271
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Like Prominin 1, Prominin 2 expression is likely to be involved in growth suppression in the prostate, Similar to Prominin1 localization, and all along the digestive track and other epithelial tissues, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth, but their genomic organization is strikingly similar, suggesting a tumor suppressive role for Prominin 2, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains, Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	Prominin 2 Polyclonal Antibody
Other name	Anti-Prominin 2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Prominin 2
Short name	Anti-Prominin 2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Prominin 2 (polyclonal)
Alternative technique	polyclonals
Identity	20685
Gene	PROM2
Long gene name	prominin 2
Locus	2q11, 1
Discovery year	2003-03-25
GenBank acession	AF245303
Entrez gene record	150696
Pubmed identfication	12514187
RefSeq identity	NM_144707
Havana BLAST/BLAT	OTTHUMG00000130393

Anti-Prominin 2 (Polyclonal), ALEXA Fluor 594

Anti-Prominin 2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Similar products

Subscribe to our Newsletter