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Anti-PSMD6 (Polyclonal), ALEXA Fluor 594

Anti-PSMD6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePSMD6
SpecificityThis antibody reacts specifically with PSMD6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PSMD6/Proteasome regulatory particle subunit p44S10
Gene ID9861
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 451Lu and WM164, At specific stages of development, In addition to normal tissue expression, Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, The pUb-R2 subunit, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5), is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells, liver, originally identified as S5a, p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, p44S10 is also expressed in several melanoma cell lines, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation in vivo, selective breakdown of cellular proteins is ensured by two distinct pathways, skeletal muscle and pancreas, such as MCF-7, ubiquitination and degradation by the 26S proteasome, In eukaryotic cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms S10 p44S10 KIAA0107 Rpn7
Also known asPSMD6 Polyclonal Antibody
Other nameAnti-PSMD6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPSMD6
Short nameAnti-PSMD6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name 6 (polyclonal), ALEXA Fluor 594, macropain) 26S subunit, non-ATPase, antibody to-proteasome (prosome
Alternative techniquepolyclonals
Alternative to gene target 6, ATPase activity, BT, PSMD6 and IDBG-43018 and ENSG00000163636 and 9861, Psmd6 and IDBG-132715 and ENSMUSG00000021737 and 66413, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, macropain) 26S subunit, non-ATPase, nuclei, p42A and p44S10 and Rpn7 and S10 and SGA-113M, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0016887 and ATPase activity and molecular function this GO :0022624 and proteasome accessory complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0016887: ATPase activity, this GO :0016887: ATPase activity, 88479 and IDBG-645134 and ENSBTAG00000015112 and 538625, proteasome (prosome
Identity 9564
Gene PSMD6
Long gene name non-ATPase 6 , proteasome 26S subunit
Synonyms gene name 6 , macropain) 26S subunit, non-ATPase, proteasome (prosome
Locus 3p14, 1
Discovery year 1995-12-06
GenBank acession AF215935
Entrez gene record 9861
Pubmed identfication 10723133
RefSeq identity NM_014814
Classification Proteasome
Havana BLAST/BLAT OTTHUMG00000158765

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