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Anti-PTPN11(Tyr542) (Polyclonal), ALEXA Fluor 594

Anti-PTPN11(Tyr542) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePTPN11 Tyr542
SpecificityThis antibody reacts specifically with PTPN11(Tyr542)
ModificationPhosphorylation
Modification siteTyr542
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr542
Gene ID5781
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A second and much more widely expressed PTP with SH2 domains, HCP and SHP), SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, SHPTP2 (also designated PTP1D and Syp), Several groups have independently identified a non transmembrane PTP, and cell migration, designated SHPTP1 (also known as PTP1C, has been identified, metabolic control, such as mitogenic activation, transcription regulation, which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain, The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BPTP3 SH-PTP2 SHP-2 PTP2C SHP2
Also known asPTPN11(Tyr542) Polyclonal Antibody
Other nameAnti-PTPN11(Tyr542) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPTPN11(Tyr542)
Short nameAnti-PTPN11(Tyr542) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PTPN11(Tyr542) (polyclonal)
Alternative techniquepolyclonals
Identity 9644
Gene PTPN11
Long gene name non-receptor type 11 , protein tyrosine phosphatase
Synonyms gene NS1
Synonyms gene name Noonan syndrome 1
Locus 12q24, 13
Discovery year 1993-03-03
GenBank acession D13540
Entrez gene record 5781
Pubmed identfication 7894486 1280823
Classification Protein tyrosine phosphatases, non-receptor type SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000134334
Locus Specific Databases LRG_614

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