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Anti-PTPN7 (Ser246) (Polyclonal), ALEXA Fluor 594

Anti-PTPN7 (Ser246) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePTPN7 Ser246
SpecificityThis antibody reacts specifically with PTPN7 (Ser246)
ModificationPhosphorylation
Modification siteSer246
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from mouse PTPN7 around the phosphorylation site of Ser246
Gene ID5778
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rat (Rattus norvegicus), Mouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Multiple alternatively spliced transcript variants have been found for this gene, PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities, This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, This gene is preferentially expressed in a variety of hematopoietic cells, [provided by RefSeq], and is an early response gene in lymphokine stimulated cells, and oncogenic transformation, differentiation, mitotic cycle, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway, The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HEPTP LC-PTP
Also known asPTPN7 (Ser246) Polyclonal Antibody
Other nameAnti-PTPN7 (Ser246) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPTPN7 (Ser246)
Short nameAnti-PTPN7 (Ser246) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PTPN7 (Ser246) (polyclonal)
Alternative techniquepolyclonals
Identity 9659
Gene PTPN7
Long gene name non-receptor type 7 , protein tyrosine phosphatase
Locus 1q32, 1
Discovery year 1993-03-03
GenBank acession BC001746
Entrez gene record 5778
Pubmed identfication 1510684
RefSeq identity NM_002832
Classification Protein tyrosine phosphatases, non-receptor type
Havana BLAST/BLAT OTTHUMG00000035931

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