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Anti-RAB10 (Polyclonal), ALEXA Fluor 594

Anti-RAB10 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRAB10
SpecificityThis antibody reacts specifically with RAB10
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RAB10
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Accumulating data suggests an important role for Rab proteins, R-Ras, Rap, Several members of the Rab subfamily have been identified, The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function (1-6), and Rho/Rab subfamilies, each of which is found at a particular stage of a membrane transport pathway (3-8), either in endocytosis or in biosynthetic protein transport (1, exhibit 30-60% homology with Ras p21 (1), is associated with secretory vesicles (9), the SEC4 protein, which includes the Ral/Rec, which is 40% homologous to Rab proteins, 2), The Ras-related superfamily of guanine nucleotide binding proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRAB10 Polyclonal Antibody
Other nameAnti-RAB10 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRAB10
Short nameAnti-RAB10 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RAB10 (polyclonal)
Alternative techniquepolyclonals
Identity 9759
Gene RAB10
Long gene name RAB10, member RAS oncogene family
Synonyms name ras-related GTP-binding protein
Locus 2p23, 3
Discovery year 1999-07-30
GenBank acession AF106681
Entrez gene record 10890
Pubmed identfication 7688123
RefSeq identity NM_016131
Classification RAB, member RAS oncogene GTPases
Havana BLAST/BLAT OTTHUMG00000094796

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