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Anti-Rad17 (Polyclonal), ALEXA Fluor 594

Anti-Rad17 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRad17
SpecificityThis antibody reacts specifically with Rad17
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Rad17
Gene ID5884
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Jul 2013], Multiple alternatively spliced transcript variants of this gene, The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage, This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, This protein shares strong similarity with DNA replication factor C (RFC), Two pseudogenes, [provided by RefSeq, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage, and can form a complex with RFCs, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells, have been identified, have been reported, located on chromosomes 7 and 13, which encode four distinct protein isoforms, which may be required for its phosphorylation, The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Rad24 RAD17Sp CCYC
Also known asRad17 Polyclonal Antibody
Other nameAnti-Rad17 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRad17
Short nameAnti-Rad17 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Rad17 (polyclonal)
Alternative techniquepolyclonals
Identity 9807
Gene RAD17
Long gene name RAD17 checkpoint clamp loader component
Synonyms gene name RAD1 (S, pombe) , pombe) homolog RAD17 homolog (S
Locus 5q13, 2
Discovery year 1998-07-31
GenBank acession AF085736
Entrez gene record 5884
Pubmed identfication 9869296 9660800
RefSeq identity NM_133344
Havana BLAST/BLAT OTTHUMG00000099357

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