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Anti-Radical Fringe (Polyclonal), ALEXA Fluor 594

Anti-Radical Fringe (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRadical Fringe
SpecificityThis antibody reacts specifically with Radical Fringe
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Radical Fringe
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Each mammalian Fringe displays different patterns of expression, Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation, Lunatic Fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock, Manic, Manic Fringe, Playing a key role in the development of the limb bud, Radical Fringe, Radical Fringe transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor, Radical and Lunatic Fringe, a protein involved in development, also involved in somatic development, also known as Beta-1, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice, have been identified as proteins related to Drosophila Fringe, is a 331 amino acid single-pass type II membrane protein that localizes to the membrane of the Golgi apparatus, though all are expressed in the mouse embryo as well as in many adult tissues, 3-N-acetylglucosaminyltransferase Radical Fringe, Three mammalian fringe family members
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRadical Fringe Polyclonal Antibody
Other nameAnti-Radical Fringe Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRadical Fringe
Short nameAnti-Radical Fringe (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Radical Fringe (polyclonal)
Alternative techniquepolyclonals
Identity 9974
Gene RFNG
Long gene name RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyms gene name radical fringe (Drosophila) homolog radical fringe homolog (Drosophila)
Locus 17q25, 3
Discovery year 1997-11-07
GenBank acession BC069034
Entrez gene record 5986
Pubmed identfication 9187150
RefSeq identity NM_002917
Classification Beta 3-glycosyltransferases
Havana BLAST/BLAT OTTHUMG00000178512

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