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Anti-RAE1 (Polyclonal), ALEXA Fluor 594

Anti-RAE1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRAE1
SpecificityThis antibody reacts specifically with RAE1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RAE1
Gene ID8480
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternatively spliced transcript variants encoding the same protein have been found for this gene, Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly, It contains four WD40 motifs, This gene is thought to be involved in nucleocytoplasmic transport, and has been shown to localize to distinct foci in the nucleoplasm, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton, and to meshwork-like structures throughout the cytoplasm, suggesting that the encoded proteins are involved in RNA export, to the nuclear rim, Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Mnrp41
Also known asRAE1 Polyclonal Antibody
Other nameAnti-RAE1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRAE1
Short nameAnti-RAE1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RAE1 (polyclonal)
Alternative techniquepolyclonals
Identity 9828
Gene RAE1
Long gene name ribonucleic acid export 1
Synonyms gene name RAE1 (RNA export 1, S, pombe) , pombe) homolog RAE1 RNA export 1 homolog (S
Locus 20q13, 31
Discovery year 1999-07-23
GenBank acession U84720
Entrez gene record 8480
Pubmed identfication 9370289 9256445
Classification Nucleoporins WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000032819

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