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Anti-RanBP2 (Polyclonal), ALEXA Fluor 594

Anti-RanBP2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRanBP2
SpecificityThis antibody reacts specifically with RanBP2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RanBP2
Gene ID5903
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In humans, Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells, Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmic transport processes, Ran-binding protein 2 (Ran BP-2 or Nup358), This genetic heterogeneity renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia, contains four Ran-binding domains, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q, The nuclear pore complex protein
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NUP358 ADANE
Also known asRanBP2 Polyclonal Antibody
Other nameAnti-RanBP2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRanBP2
Short nameAnti-RanBP2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RanBP2 (polyclonal)
Alternative techniquepolyclonals
Identity 9848
Gene RANBP2
Long gene name RAN binding protein 2
Synonyms gene ANE1
Synonyms gene name acute necrotizing encephalopathy 1 (autosomal dominant)
Synonyms name nucleoporin 358
Locus 2q13
Discovery year 1996-11-14
GenBank acession D42063
Entrez gene record 5903
Pubmed identfication 7724562 19118815
RefSeq identity NM_006267
Classification Zinc fingers RANBP2-type Tetratricopeptide repeat domain containing Cyclophilin peptidylprolyl isomerases Nucleoporins
Havana BLAST/BLAT OTTHUMG00000130981

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