Anti-RanBP3 (Polyclonal), Biotin

Anti-RanBP3 (Polyclonal), Biotin size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	Biotin
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	RanBP3
Specificity	This antibody reacts specifically with RanBP3 Biotin
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Nucleus, Cytoplasm
Antigen Source	KLH conjugated synthetic peptide derived from human RanBP3
Gene ID	8498
Swiss Prot	Q9H6Z4
Applications	IHC-P, WB
Applications with corresponding dilutions	IHC-P(1:100-500), WB(1:100-1000)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1, Bound to XPO1/CRM1, In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex, Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner, SMAD2 and SMAD3, and mediating their nuclear export, perhaps as export complex scaffolding protein, stabilizes the XPO1/CRM1-cargo interaction, Acts as a cofactor for XPO1/CRM1-mediated nuclear export
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	N/A
Also known as	RanBP3 Polyclonal Antibody Biotin
Other name	Anti-RanBP3 Polyclonal Biotin
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase
Conjugation	Biotinylated
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	RanBP3
Short name	Anti-RanBP3 (Polyclonal)
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	Biotin
Alternative name	biotinilated, antibody to-RanBP3 (polyclonal)
Alternative technique	polyclonals
Identity	9850
Gene	RANBP3
Long gene name	RAN binding protein 3
Locus	19p13, 3
Discovery year	1998-11-30
GenBank acession	Y08698
Entrez gene record	8498
Pubmed identfication	9637251
RefSeq identity	NM_007322
Havana BLAST/BLAT	OTTHUMG00000180636

Anti-RanBP3 (Polyclonal), Biotin

Anti-RanBP3 (Polyclonal), Biotin size: 100 microliters 489

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