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Anti-RanBP3 (Polyclonal), Cy3

Anti-RanBP3 (Polyclonal), Cy3 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated withCy3
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRanBP3
SpecificityThis antibody reacts specifically with RanBP3 Cy3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human RanBP3
Gene ID8498
Swiss ProtQ9H6Z4
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1, Bound to XPO1/CRM1, In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex, Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner, SMAD2 and SMAD3, and mediating their nuclear export, perhaps as export complex scaffolding protein, stabilizes the XPO1/CRM1-cargo interaction, Acts as a cofactor for XPO1/CRM1-mediated nuclear export
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission512, 550nm/570, 615nm
Also known asRanBP3 Polyclonal Antibody Cy3
Other nameAnti-RanBP3 Polyclonal Cy3
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties 1 of the Anti-RanBP3 (Polyclonal) can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, This Bioss Polyclonal Antibodies antibody is well suited for fluorescent microscopy, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser
Conjugationcy3 conjugation kit
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRanBP3
Short nameAnti-RanBP3 (Polyclonal)
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelCy3
Alternative name cyanine 3, antibody to-RanBP3 (polyclonal)
Alternative techniquepolyclonals
Identity 9850
Gene RANBP3
Long gene name RAN binding protein 3
Locus 19p13, 3
Discovery year 1998-11-30
GenBank acession Y08698
Entrez gene record 8498
Pubmed identfication 9637251
RefSeq identity NM_007322
Havana BLAST/BLAT OTTHUMG00000180636

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