Name : Anti-RAPGEF2/PDZ-GEF1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1348420490
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RAPGEF2/PDZ-GEF1 |
| Specificity | This antibody reacts specifically with RAPGEF2/PDZ-GEF1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human RAPGEF2 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expressed at highest levels in brain, PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, PDZ-GEF1 is found at low levels in placenta, Rap 1B and Rap 2B GTPases, The gene encoding PDZ-GEF1 maps to human chromosome 4q32, a Ras-associating domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain, and undergoes post-translational phosphorylation following DNA damage, heart, lung and kidney, one PDZ (DHR) domain, 1, 499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, PDZ-GEF1 is a 1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PDZ-GEF1 RA-GEF DKFZP586O1422 KIAA0313 |
| Also known as | RAPGEF2/PDZ-GEF1 Polyclonal Antibody |
| Other name | Anti-RAPGEF2/PDZ-GEF1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RAPGEF2/PDZ-GEF1 |
| Short name | Anti-RAPGEF2/PDZ-GEF1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-RAPGEF2/PDZ-GEF1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 16854 |
| Gene | RAPGEF2 |
| Long gene name | Rap guanine nucleotide exchange factor 2 |
| Synonyms gene | PDZGEF1 |
| Synonyms gene name | PDZ domain containing guanine nucleotide exchange factor (GEF) 1 Rap guanine nucleotide exchange factor (GEF) 2 |
| Synonyms name | Rap GEP |
| Locus | 4q32, 1 |
| Discovery year | 2003-05-20 |
| GenBank acession | AB002311 |
| Entrez gene record | 9693 |
| Pubmed identfication | 9205841 10934204 |
| RefSeq identity | NM_014247 |
| Classification | PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000161451 |