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Anti-Raptor (Ser792) (Polyclonal), ALEXA Fluor 594

Anti-Raptor (Ser792) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRaptor Ser792
SpecificityThis antibody reacts specifically with Raptor (Ser792)
ModificationPhosphorylation
Modification siteSer792
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from mouse Raptor around the phosphorylation site of Ser792
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro, RNAi of C, Rapamycin or amino acid withdrawal increases, Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha, The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, Thus, and it strongly enhances the mTOR kinase activity toward p70alpha, elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1), raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose, whereas insulin strongly inhibits, mTOR controls cell growth
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1303, P150 target of rapamycin TOR-scaffold protein, RPTOR_HUMAN, Raptor phospho Ser792, Regulatory Associated Protein of mTOR, Regulatory-associated protein of mTOR, p-Raptor Ser792, p150 target of rapamycin TOR scaffold protein containing WD repeats, p150 target of rapamycin TOR-scaffold protein, ARaptor phospho S792
Also known asRaptor (Ser792) Polyclonal Antibody
Other nameAnti-Raptor (Ser792) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRaptor (Ser792)
Short nameAnti-Raptor (Ser792) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Raptor (Ser792) (polyclonal)
Alternative techniquepolyclonals

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