Anti-Rb/P105 RB (Thr821) (Polyclonal), ALEXA Fluor 594

Anti-Rb/P105 RB (Thr821) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Rb/P105 RB Thr821
Specificity	This antibody reacts specifically with Rb/P105 RB (Thr821)
Modification	Phosphorylation
Modification site	Thr821
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Thr821
Gene ID	5925
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	LYT-10 p52 p105 NF-kB2 p49/p100
Also known as	Rb/P105 RB (Thr821) Polyclonal Antibody
Other name	Anti-Rb/P105 RB (Thr821) Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Rb/P105 RB (Thr821)
Short name	Anti-Rb/P105 RB (Thr821) (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Rb/P105 RB (Thr821) (polyclonal)
Alternative technique	polyclonals
Identity	7795
Gene	NFKB2
Long gene name	nuclear factor kappa B subunit 2
Synonyms gene name	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Locus	10q24, 32
Discovery year	1991-11-14
GenBank acession	X61498
Entrez gene record	4791
Pubmed identfication	1876189
Classification	Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT	OTTHUMG00000018962

Anti-Rb/P105 RB (Thr821) (Polyclonal), ALEXA Fluor 594

Anti-Rb/P105 RB (Thr821) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

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