Name : Anti-RCBTB1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2561683374
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RCBTB1 |
| Specificity | This antibody reacts specifically with RCBTB1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human RCBTB1/CLLD7 |
| Gene ID | 55213 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CLLD7, CLLL7 or E4, Expressed ubiquitously, Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function, RCBTB1 (regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1), RCBTB1 is thought to be involved in cell cycle regulation, The gene encoding RCBTB1 maps to a region on human chromosome 13 that is frequently deleted in B-cell chronic lymphocytic leukemia, also known as GLP, also known as the POZ (poxvirus and zinc finger) domain, is a 531 amino acid protein that localizes to the nucleus and contains two BTB (POZ) domains and six RCC1 repeats, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers, specifically via chromatin remodeling, suggesting a possible role for RCBTB1 in tumor suppression, 5, The BTB domain |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ10716 CLLD7 CLLL7 |
| Also known as | RCBTB1 Polyclonal Antibody |
| Other name | Anti-RCBTB1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RCBTB1 |
| Short name | Anti-RCBTB1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-RCBTB1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 18243 |
| Gene | RCBTB1 |
| Long gene name | RCC1 and BTB domain containing protein 1 |
| Synonyms gene name | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| Locus | 13q14, 2 |
| Discovery year | 2003-05-02 |
| GenBank acession | AF334406 |
| Entrez gene record | 55213 |
| Pubmed identfication | 11306461 |
| RefSeq identity | NM_018191 |
| Classification | BTB domain containing |
| Havana BLAST/BLAT | OTTHUMG00000016915 |