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Anti-RECQL5 (Polyclonal), ALEXA Fluor 594

Anti-RECQL5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRECQL5
SpecificityThis antibody reacts specifically with RECQL5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RECQL5
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), RecQL5 is one of five known RecQ homologues in humans, The exact role of ReqL5 is unclear, There are three different RecQL5 isoforms - alpha, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer, and defects in three of these (BLM, beta and gamma, produced by alternative splicing, whereas deleting Recql5 lead to an even higher frequency of SCE, RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RecQ5 FLJ90603
Also known asRECQL5 Polyclonal Antibody
Other nameAnti-RECQL5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRECQL5
Short nameAnti-RECQL5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RECQL5 (polyclonal)
Alternative techniquepolyclonals
Identity 9950
Gene RECQL5
Long gene name RecQ like helicase 5
Synonyms name RecQ protein 5
Locus 17q25
Discovery year 1999-05-06
GenBank acession AB006533
Entrez gene record 9400
Pubmed identfication 9878247
RefSeq identity NM_004259
Classification RecQ like helicases
Havana BLAST/BLAT OTTHUMG00000179795

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