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Anti-RhoA/C(Polyclonal), ALEXA Fluor 594

Anti-RhoA/C(Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRhoA/C
SpecificityThis antibody reacts specifically with RhoA/CPolyclonal
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Helical, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human RhoA
Gene ID387, 389
Swiss ProtP61586
Applications IF(ICC), IF(IHC-P)
Applications with corresponding dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activated by ARHGEF2, Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly, In turn, Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis, It controls the localization of APC and CLASP2 to the cell membrane, May be an activator of PLCE1, Plays an essential role in cleavage furrow formation, Required for the apical junction formation of keratinocyte cell-cell adhesion, Serves as a target for the yopT cysteine peptidase from Yersinia pestis, Stimulates PKN2 kinase activity, The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex, and Yersinia pseudotuberculosis, membrane-bound APC allows the localization of the MACF1 to the cell membrane, vector of the plague, via the regulation of GSK3B activity, which causes gastrointestinal disorders, which is required for microtubule capture and stabilization, which promotes the exchange of GDP for GTP, Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ARH12, ARH9, ARHC, RHO12, RHOA, RHOH12, Rho cDNA clone 12, Rho cDNA clone 9, Rho-related GTP-binding protein RhoC, Transforming protein RhoA, h12, ARHA
Also known asRhoA/CPolyclonal Antibody
Other nameAnti-RhoA/CPolyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRhoA/C
Short nameAnti-RhoA/C(Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ras homolog family member A/C(polyclonal)
Alternative techniquepolyclonals

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