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Anti-RNF135 (Polyclonal), ALEXA Fluor 594

Anti-RNF135 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF135
SpecificityThis antibody reacts specifically with RNF135
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF135
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, Multiple isoforms of RNF135 exist due to alternative splicing events, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF135 (RING finger protein 135), RNF135 may play a role in transcriptional regulation and protein degradation events, Via its RING-type zinc finger, also known as L13, facial dysmorphism and increased weight and height, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MGC13061
Also known asRNF135 Polyclonal Antibody
Other nameAnti-RNF135 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF135
Short nameAnti-RNF135 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ring finger protein 135 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, Cytoplasm, RNF135 and IDBG-39370 and ENSG00000181481 and 84282, Rnf135 and IDBG-204021 and ENSMUSG00000020707 and 71956, metal ion binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0043021 and ribonucleoprotein complex binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0043021: ribonucleoprotein complex binding and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0043021: ribonucleoprotein complex binding, this GO :0046872: metal ion binding, 65952 and IDBG-631087 and ENSBTAG00000017225 and 511125, ring finger protein 135
Identity 21158
Gene RNF135
Long gene name ring finger protein 135
Synonyms name riplet
Locus 17q11, 2
Discovery year 2003-05-21
GenBank acession AJ496729
Entrez gene record 84282
Pubmed identfication 11468690 19017631
RefSeq identity NM_032322
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000132867
Locus Specific Databases LOVD - Leiden Open Variation Database

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