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Anti-RNF139 (Polyclonal), ALEXA Fluor 594

Anti-RNF139 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF139
SpecificityThis antibody reacts specifically with RNF139
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF139
Gene ID11236
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer, This protein is located in the endoplasmic reticulum, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP, and has been shown to possess ubiquitin ligase activity, as well as with COPS5/JAB1, The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms TRC8 RCA1 HRCA1
Also known asRNF139 Polyclonal Antibody
Other nameAnti-RNF139 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF139
Short nameAnti-RNF139 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF139 (polyclonal)
Alternative techniquepolyclonals
Identity 17023
Gene RNF139
Long gene name ring finger protein 139
Locus 8q24, 13
Discovery year 2003-05-21
GenBank acession AF064801
Entrez gene record 11236
Pubmed identfication 9689122
RefSeq identity NM_007218
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000165072

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