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Anti-RNF144B (Polyclonal), ALEXA Fluor 594

Anti-RNF144B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF144B
SpecificityThis antibody reacts specifically with RNF144B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B
Gene ID255488
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information But, However, Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism, a pro-apoptotic protein, and highest levels detectable in heart, it is not an anti-apoptotic protein per se, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, ovary and testis, thereby promoting their degradation, ultimately leading to protection of cell death, with lowest levels in brain and thymus, E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, Tissue specificity: Broadly expressed
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms bA528A10, 3 P53RFP
Also known asRNF144B Polyclonal Antibody
Other nameAnti-RNF144B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF144B
Short nameAnti-RNF144B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ring finger protein 144B (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, Plasma membranes, RNF144B and IDBG-64050 and ENSG00000137393 and 255488, Rnf144b and IDBG-149475 and ENSMUSG00000038068 and 218215, ligase activity, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016874 and ligase activity and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, 66635 and IDBG-635837 and ENSBTAG00000009055 and 524166, ring finger protein 144B
Identity 21578
Gene RNF144B
Long gene name ring finger protein 144B
Synonyms gene IBRDC2
Synonyms gene name IBR domain containing 2
Locus 6p22, 3
Discovery year 2003-06-25
GenBank acession AK096832
Entrez gene record 255488
RefSeq identity XM_172581
Classification Ring finger proteins RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000014322

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