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Anti-RNF158 (Polyclonal), ALEXA Fluor 594

Anti-RNF158 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF158
SpecificityThis antibody reacts specifically with RNF158
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF158
Gene ID153769
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Due to alternative splicing events, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, SH3RF2 (SH3 domain containing ring finger 2), SH3RF2 binds an E2 ubiquitin-conjugating enzyme, SH3RF2 is expressed as two different isoforms, This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation, Via its RING-type zinc finger domain, also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ23654 RNF158 Hepp1 POSHER
Also known asRNF158 Polyclonal Antibody
Other nameAnti-RNF158 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF158
Short nameAnti-RNF158 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF158 (polyclonal)
Alternative techniquepolyclonals
Identity 26299
Gene SH3RF2
Long gene name SH3 domain containing ring finger 2
Synonyms gene PPP1R39
Synonyms gene name protein phosphatase 1, regulatory subunit 39
Synonyms name heart protein phosphatase 1-binding protein POSH-eliminating RING protein
Locus 5q32
Discovery year 2004-03-05
GenBank acession AL833297
Entrez gene record 153769
Pubmed identfication 22128169
RefSeq identity NM_152550
Classification Ring finger proteins Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000129685

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