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Anti-RNF180 (Polyclonal), ALEXA Fluor 594

Anti-RNF180 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF180
SpecificityThis antibody reacts specifically with RNF180
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF180
Gene ID285671
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, Expressed as three alternatively spliced isoforms, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF180 (ring finger protein 180), RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway, RNF180 is encoded by a gene located on human chromosome 5, RNF180 is expressed in brain, RNF180 is well conserved among vertebrates, also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome, kidney, or of chromosome 5 altogether, testis and uterus and localizes to the endoplasmic reticulum, which contains 181 million base pairs and comprises nearly 6% of the human genome, while deletion of the q arm, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRNF180 Polyclonal Antibody
Other nameAnti-RNF180 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF180
Short nameAnti-RNF180 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF180 (polyclonal)
Alternative techniquepolyclonals
Identity 27752
Gene RNF180
Long gene name ring finger protein 180
Locus 5q12, 3
Discovery year 2005-01-26
GenBank acession AK090756
Entrez gene record 285671
RefSeq identity NM_178532
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000162278

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