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Anti-RNF185 (Polyclonal), ALEXA Fluor 594

Anti-RNF185 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF185
SpecificityThis antibody reacts specifically with RNF185
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF185
Gene ID91445
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF185 (ring finger protein 185), Two RNF185 isoforms exist as a result of alternative splicing, also known as FLJ38628, and the gene encoding RNF185 maps to human chromosome 22, autism and schizophrenia, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger, which houses over 500 genes and is the second smallest human chromosome, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ38628
Also known asRNF185 Polyclonal Antibody
Other nameAnti-RNF185 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF185
Short nameAnti-RNF185 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF185 (polyclonal)
Alternative techniquepolyclonals
Identity 26783
Gene RNF185
Long gene name ring finger protein 185
Synonyms name hypothetical protein FLJ38628
Locus 22q12, 2
Discovery year 2005-03-31
Entrez gene record 91445
Pubmed identfication 12477932
RefSeq identity NM_152267
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000151253

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