Name : Anti-RNF186 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3191833452
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RNF186 |
| Specificity | This antibody reacts specifically with RNF186 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human RNF186 |
| Gene ID | 54546 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome, Gaucher disease and Usher syndrome are also associated with chromosome 1, Notably, Parkinsons, RNF186 (RING finger protein 186) is a 227 amino acid multi-pass membrane protein containing one RING-type zinc finger, Stickler syndrome, The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis, The gene encoding RNF186 maps to human chromosome 1p36, The ring finger protein (RNF) family includes any protein containing the signature RING finger motif, There are about 3, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A, 000 genes on chromosome 1, 13, The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ20225 |
| Also known as | RNF186 Polyclonal Antibody |
| Other name | Anti-RNF186 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RNF186 |
| Short name | Anti-RNF186 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-RNF186 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25978 |
| Gene | RNF186 |
| Long gene name | ring finger protein 186 |
| Synonyms name | hypothetical protein FLJ20225 |
| Locus | 1p36, 13 |
| Discovery year | 2005-03-31 |
| Entrez gene record | 54546 |
| Pubmed identfication | 12477932 |
| RefSeq identity | NM_019062 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000002709 |