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Anti-RNF186 (Polyclonal), ALEXA Fluor 594

Anti-RNF186 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF186
SpecificityThis antibody reacts specifically with RNF186
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF186
Gene ID54546
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome, Gaucher disease and Usher syndrome are also associated with chromosome 1, Notably, Parkinsons, RNF186 (RING finger protein 186) is a 227 amino acid multi-pass membrane protein containing one RING-type zinc finger, Stickler syndrome, The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis, The gene encoding RNF186 maps to human chromosome 1p36, The ring finger protein (RNF) family includes any protein containing the signature RING finger motif, There are about 3, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A, 000 genes on chromosome 1, 13, The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ20225
Also known asRNF186 Polyclonal Antibody
Other nameAnti-RNF186 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF186
Short nameAnti-RNF186 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF186 (polyclonal)
Alternative techniquepolyclonals
Identity 25978
Gene RNF186
Long gene name ring finger protein 186
Synonyms name hypothetical protein FLJ20225
Locus 1p36, 13
Discovery year 2005-03-31
Entrez gene record 54546
Pubmed identfication 12477932
RefSeq identity NM_019062
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000002709

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