Name : Anti-RNF23 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8008929860
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RNF23 |
| Specificity | This antibody reacts specifically with RNF23 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human RNF23 |
| Gene ID | 56658 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF23 (RING finger protein 23), RNF23 contains one B box-type zinc finger, RNF23 is found at highest levels in spleen, RNF23 typically localizes to cytosol but shifts to mitochondria upon co-localization with MOAP1, Ubiquitously expressed and existing as two alternatively spliced isoforms, a B30, a short-lived, also known as tripartite motif-containing protein 39 (TRIM39) or testis-abundant finger protein, brain, heart and skeletal muscle, is a 518 amino acid protein belonging to the TRIM/RBCC family that is known to interact with MOAP1, kidney, liver, pro-apoptotic protein which RNF23 prevents from becoming poly-ubiquitinated and degraded, testis, thereby facilitating apoptosis, 2/SPRY domain and a single RING-type zinc finger, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | RNF23 Polyclonal Antibody |
| Other name | Anti-RNF23 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RNF23 |
| Short name | Anti-RNF23 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-RNF23 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 10065 |
| Gene | TRIM39 |
| Long gene name | tripartite motif containing 39 |
| Synonyms gene | RNF23 |
| Synonyms gene name | ring finger protein 23 tripartite motif-containing 39 |
| Locus | 6p22, 1 |
| Discovery year | 2000-07-31 |
| GenBank acession | BC034985 |
| Entrez gene record | 56658 |
| Pubmed identfication | 11006080 |
| RefSeq identity | NM_172016 |
| Classification | Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000031066 |