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Anti-RNF23 (Polyclonal), ALEXA Fluor 594

Anti-RNF23 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF23
SpecificityThis antibody reacts specifically with RNF23
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RNF23
Gene ID56658
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF23 (RING finger protein 23), RNF23 contains one B box-type zinc finger, RNF23 is found at highest levels in spleen, RNF23 typically localizes to cytosol but shifts to mitochondria upon co-localization with MOAP1, Ubiquitously expressed and existing as two alternatively spliced isoforms, a B30, a short-lived, also known as tripartite motif-containing protein 39 (TRIM39) or testis-abundant finger protein, brain, heart and skeletal muscle, is a 518 amino acid protein belonging to the TRIM/RBCC family that is known to interact with MOAP1, kidney, liver, pro-apoptotic protein which RNF23 prevents from becoming poly-ubiquitinated and degraded, testis, thereby facilitating apoptosis, 2/SPRY domain and a single RING-type zinc finger, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRNF23 Polyclonal Antibody
Other nameAnti-RNF23 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF23
Short nameAnti-RNF23 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF23 (polyclonal)
Alternative techniquepolyclonals
Identity 10065
Gene TRIM39
Long gene name tripartite motif containing 39
Synonyms gene RNF23
Synonyms gene name ring finger protein 23 tripartite motif-containing 39
Locus 6p22, 1
Discovery year 2000-07-31
GenBank acession BC034985
Entrez gene record 56658
Pubmed identfication 11006080
RefSeq identity NM_172016
Classification Tripartite motif containing Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000031066

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