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Anti-RNF56 (Polyclonal), ALEXA Fluor 594

Anti-RNF56 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF56
SpecificityThis antibody reacts specifically with RNF56
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human RNF56/CBL-B
Gene ID868
Swiss ProtQ13191
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Also acts by promoting PIK3R1/p85 ubiquitination, BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In B-cells, In activated T-cells, In naive T-cells, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, May be involved in EGFR ubiquitination and internalization, Negatively regulates TCR (T-cell receptor), Slightly promotes SRC ubiquitination, acts by ubiquitinating SYK and promoting its proteasomal degradation, and transfers it to substrates, generally promoting their degradation by the proteasome, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, which impairs its recruitment to the TCR and subsequent activation, E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RNF56 Cbl-b
Also known asRNF56 Polyclonal Antibody
Other nameAnti-RNF56 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF56
Short nameAnti-RNF56 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF56 (polyclonal)
Alternative techniquepolyclonals
Identity 1542
Gene CBLB
Long gene name Cbl proto-oncogene B
Synonyms gene name Cas-Br-M (murine) ectropic retroviral transforming sequence b Cas-Br-M (murine) ecotropic retroviral transforming sequence b Cbl proto-oncogene B, E3 ubiquitin protein ligase
Locus 3q13, 11
Discovery year 1995-12-18
GenBank acession U26710
Entrez gene record 868
Pubmed identfication 7784085
RefSeq identity NM_170662
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000150654

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