Name : Anti-RNF62 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4323983867
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RNF62 |
| Specificity | This antibody reacts specifically with RNF62 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human MKRN2/RNF62 |
| Gene ID | 23609 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | HSPC070 or MKRN2, In Xenopus, In addition, In addition, In humans, Makorin-2, Makorin-2 functions, Makorin-2 is co-expressed with Raf-1 in the same tissues and cell lines, Makorin-2 is overexpressed in various cancer cell lines, also known as RNF62, as a negative regulator of neurogenesis, evolutionarily conserved protein with four C3H-type zinc fingers (three at the N-terminus and one at the C-terminus), is a widely expressed, one RING-type zinc finger and a cysteine and histidine motif similar to that found in Makorin-1, suggesting a possible role of Makorin-2 in tumor progression, they contain a C3HC4 RING zinc finger that allows them to function as E3 ubiquitin ligases, via PI 3-kinase/Akt signaling, The Makorins are a family of putative ribonucleoproteins containing two to four C3H zinc fingers that may confer RNA-binding |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RNF62 HSPC070 |
| Also known as | RNF62 Polyclonal Antibody |
| Other name | Anti-RNF62 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RNF62 |
| Short name | Anti-RNF62 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-RNF62 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 7113 |
| Gene | MKRN2 |
| Long gene name | makorin ring finger protein 2 |
| Locus | 3p25, 2 |
| Discovery year | 1999-10-19 |
| Entrez gene record | 23609 |
| Pubmed identfication | 11597136 |
| RefSeq identity | NM_014160 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000155371 |