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Anti-ROR beta (Polyclonal), ALEXA Fluor 594

Anti-ROR beta (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideROR beta
SpecificityThis antibody reacts specifically with ROR beta
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human RORB
Gene ID6096
Swiss ProtQ92753
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Considered to have intrinsic transcriptional activity, In cone photoreceptor cells, Involved in the regulation of the period length and stability of the circadian rhythm, May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons, May control cytoarchitectural patterning of neocortical neurons during development, May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity), Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway, Required for normal postnatal development of rod and cone photoreceptor cells, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity, regulates transcription of OPN1SW, Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms lincRNA-RoR lincRNA-ST8SIA3 ROR
Also known asROR beta Polyclonal Antibody
Other nameAnti-ROR beta Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetROR beta
Short nameAnti-ROR beta (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ROR b (polyclonal)
Alternative techniquepolyclonals
Identity 43773
Gene LINC-ROR
Long gene name long intergenic non-protein coding RNA, regulator of reprogramming
Locus 18q21, 31
Discovery year 2012-05-01
GenBank acession HQ315778
Entrez gene record 100885779
Pubmed identfication 21057500 23208419 23541921 23597480 24463816
RefSeq identity NR_048536
Classification Long non-coding RNAs Competing endogenous long non-coding RNAs
Havana BLAST/BLAT OTTHUMG00000171587

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