Anti-RPA70 (Polyclonal), ALEXA Fluor 594

Anti-RPA70 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	RPA70
Specificity	This antibody reacts specifically with RPA70
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human RPA70
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	It can also play a role in telomere maintenance, RPA contains a conserved four cysteine-type zinc-finger motif, RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair, RPA plays an important role in DNA replication, Replication protein A (RPA), The DNA binding domain lies in the middle of RPA 70 kDa subunit and comprises two structurally homologous subdomains oriented in tandem, The RPA 70 kDa subunit binds to ssDNA and mediates interactions with many cellular and viral proteins, The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of an ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA, a highly conserved eukaryotic protein, is a heterotrimeric SSB, mitochondria, phages and viruses, recombination and repair, which mediates the transition of RPA-ssDNA interaction to a stable RPA-ssDNA complex in a redox-dependent manner, The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	REPA1 RPA70 HSSB RF-A RP-A
Also known as	RPA70 Polyclonal Antibody
Other name	Anti-RPA70 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	RPA70
Short name	Anti-RPA70 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-RPA70 (polyclonal)
Alternative technique	polyclonals
Identity	10289
Gene	RPA1
Long gene name	replication protein A1
Synonyms gene name	70kDa , replication protein A1 (70kD) replication protein A1
Locus	17p13, 3
Discovery year	1993-12-14
GenBank acession	M63488
Entrez gene record	6117
Pubmed identfication	8454588
RefSeq identity	NM_002945
Classification	Nucleotide excision repair
Havana BLAST/BLAT	OTTHUMG00000090579

Anti-RPA70 (Polyclonal), ALEXA Fluor 594

Anti-RPA70 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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