Anti-RPE65 (Polyclonal), ALEXA Fluor 594

Anti-RPE65 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	RPE65
Specificity	This antibody reacts specifically with RPE65
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human RPE65
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2, RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated, Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the Î, The soluble form of the protein binds vitamin A, This protein is important in 11-cis retinal production as well as in visual pigment regeneration, ², -carotene dioxygenase family, The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	LCA2 rd12 BCO3
Also known as	RPE65 Polyclonal Antibody
Other name	Anti-RPE65 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	RPE65
Short name	Anti-RPE65 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-RPE65 (polyclonal)
Alternative technique	polyclonals
Identity	10294
Gene	RPE65
Long gene name	RPE65, retinoid isomerohydrolase
Synonyms gene	RP20
Synonyms gene name	retinal pigment epithelium-specific protein 65kDa
Synonyms name	BCO family, member 3 retinol isomerase all-trans-retinyl-palmitate hydrolase
Locus	1p31, 3
Discovery year	1993-10-04
GenBank acession	U18991
Entrez gene record	6121
Pubmed identfication	8340400 16116091
RefSeq identity	NM_000329
Havana BLAST/BLAT	OTTHUMG00000009208
Locus Specific Databases	Mutations of the RPE65 Gene

Anti-RPE65 (Polyclonal), ALEXA Fluor 594

Anti-RPE65 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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