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Anti-RPS6KA1(Thr359) (Polyclonal), ALEXA Fluor 594
Anti-RPS6KA1(Thr359) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516
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BIOSS POLYCLONAL ANTIBODIES
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516
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RPS6KA1 Thr359 |
| Specificity | This antibody reacts specifically with RPS6KA1(Thr359) |
| Modification | Phosphorylation |
| Modification site | Thr359 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human RPS6KA1 around the phosphorylation site of Thr359 |
| Gene ID | 6195 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation, Rsk2 and Rsk3, These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2, which includes Rsk1, Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RSK RSK1 HU-1 p90Rsk |
| Also known as | RPS6KA1(Thr359) Polyclonal Antibody |
| Other name | Anti-RPS6KA1(Thr359) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RPS6KA1(Thr359) |
| Short name | Anti-RPS6KA1(Thr359) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | 90kDa, ALEXA Fluor 594, polypeptide 1(Thr359) (polyclonal), antibody to-ribosomal protein S6 phosphorylation catalyst |
| Alternative technique | polyclonals |
| Alternative to gene target | 90kDa, HU-1 and MAPKAPK1A and RSK and RSK1, RPS6KA1 and IDBG-645125 and ENSBTAG00000014447 and 533908, RPS6KA1 and IDBG-94680 and ENSG00000117676 and 6195, Rps6ka1 and IDBG-195412 and ENSMUSG00000003644 and 20111, alcohol group as acceptor, alcohol group as acceptor and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, alcohol group as acceptor and molecular function this GO :0030307 and positive regulation of cell growth and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043555 and regulation of translation in response to stress and biological process this GO :0043620 and regulation of DNA-dependent transcription in response to stress and biological process this GO :0045087 and innate immune response and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :2000491 and positive regulation of hepatic stellate cell activation and biological process, nuclei, polypeptide 1, this GO :0000287 and magnesium ion binding and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007049 and cell cycle and biological process this GO :0007165 and signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004712: protein serine/threonine/tyrosine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004712: protein serine/threonine/tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0016773: phosphotransferase activity, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773: phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, ribosomal protein S6 kinase |
| Identity | 10430 |
| Gene | RPS6KA1 |
| Long gene name | ribosomal protein S6 kinase A1 |
| Synonyms gene name | 90kD, polypeptide 1 , ribosomal protein S6 kinase |
| Locus | 1p36, 11 |
| Discovery year | 1994-07-11 |
| GenBank acession | BC014966 |
| Entrez gene record | 6195 |
| Pubmed identfication | 8141249 |
| RefSeq identity | NM_002953 |
| Classification | Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000004003 |