Name : Anti-RUSC1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2957640445
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RUSC1 |
| Specificity | This antibody reacts specifically with RUSC1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human RUSC1 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions, RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation, RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK, RUSC1â, RUSC2 (RUN and SH3 domain containing 2), RUSC2 also consists of a SH3 domain, Rab 1B and GM130, The RUN domain of RUSC2 is required for interaction with Rab 1A, also known as Iporin, is a 1, suggesting a role in protein-protein interactions, with highest levels in brain and testis, &euro, &trade, 516 amino acid cytoplasmic protein that is widely expressed, RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain, s RUN domain is necessary for NGF induced nuclear redistribution |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | NESCA |
| Also known as | RUSC1 Polyclonal Antibody |
| Other name | Anti-RUSC1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RUSC1 |
| Short name | Anti-RUSC1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-RUSC1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 17153 |
| Gene | RUSC1 |
| Long gene name | RUN and SH3 domain containing 1 |
| Locus | 1q22 |
| Discovery year | 2003-02-24 |
| GenBank acession | AB026894 |
| Entrez gene record | 23623 |
| Pubmed identfication | 10760598 |
| Havana BLAST/BLAT | OTTHUMG00000013910 |