Name : Anti-S100B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7244607589
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | S100B |
| Specificity | This antibody reacts specifically with S100B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus, Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human S100B |
| Gene ID | 6285 |
| Swiss Prot | P04271 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase, Could assist ATAD3A cytoplasmic processing, Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling, May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, Physiological concentrations of potassium ion antagonize the binding of both divalent cations, and modulating their activity, especially affecting high-affinity calcium-binding sites, preventing aggregation and favoring mitochondrial localization, such as TPR-containing proteins, Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | S100beta |
| Also known as | S100B Polyclonal Antibody |
| Other name | Anti-S100B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | S100B |
| Short name | Anti-S100B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-S100B (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 10500 |
| Gene | S100B |
| Long gene name | S100 calcium binding protein B |
| Synonyms gene name | S100 calcium binding protein, beta (neural) |
| Locus | 21q22, 3 |
| Discovery year | 1988-06-27 |
| GenBank acession | M59488 |
| Entrez gene record | 6285 |
| Pubmed identfication | 2394738 1998503 |
| RefSeq identity | NM_006272 |
| Classification | S100 calcium binding proteins EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000090715 |