Anti-S1P1 (Polyclonal), ALEXA Fluor 594

Anti-S1P1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	S1P1
Specificity	This antibody reacts specifically with S1P1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Helical, Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human S1P1
Gene ID	1901
Swiss Prot	P21453
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development, PTK2/FAK1 and MAP kinases, Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury, Plays a role in the migration of osteoclast precursor cells, Plays an important role in cell migration, Plays an important role in the regulation of sprouting angiogenesis and vascular maturation, Required for normal chemotaxis toward sphingosine 1-phosphate, Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs, Required for normal embryonic heart development and normal cardiac morphogenesis, SRC, Signaling leads to the activation of RAC1, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1, the regulation of bone mineralization and bone homeostasis (By similarity), G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	CD363, CHEDG1, D1S3362, ECGF1, EDG-1, Endothelial differentiation G-protein coupled receptor 1, S1P receptor 1, S1P receptor Edg-1, S1P1, S1PR1, Sphingosine 1-phosphate receptor 1, Sphingosine 1-phosphate receptor Edg-1, EDG1
Also known as	S1P1 Polyclonal Antibody
Other name	Anti-S1P1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	S1P1
Short name	Anti-S1P1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-S1P1 (polyclonal)
Alternative technique	polyclonals

Anti-S1P1 (Polyclonal), ALEXA Fluor 594

Anti-S1P1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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